| Pronunciation: | | 'nooklee`eys
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 WordNet Dictionary |
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| | Definition: | |
[n] general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units |
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NUCLEASE is a 8 letter word that starts with N. |
| | See Also: | | endonuclease, enzyme, exonuclease |
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| Biology Dictionary |
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| | Definition: | | An enzyme that breaks down the linkages (phosphodiesters) between nucleic acids in a nucleotide chain. |
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| Glossary |
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| | Definition: | | A class of enzymes that degrades DNA and/or RNA molecules by cleaving the phosphodiester bonds that link adjacent nucleotides. In deoxyribonuclease (DNase), the substrate is DNA. In endonuclease, it cleaves at internal sites in the substrate molecule. Exonuclease progressively cleaves from the end of the substrate molecule. In ribonuclease (RNase), the substrate is RNA. In the S1 nuclease, the substrate is single-stranded DNA or RNA. |
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